Weill Cornell Medical College The Rockefeller University Memorial Sloan-Kettering Cancer Center

Apply Online Application Due: December 1, 2013

TPCB Faculty

Michael Rout, PhD

Rockefeller University


PhD, 1990, University of Cambridge

MA, 1990, University of Cambridge

BS, 1986, University of Cambridge

Research Topics

  • Macromolecular Structure and Function
    • X-ray crystallography
    • NMR spectroscopy
    • Mass spectrometry
    • Cryo-electron microscopy
    • Single molecule methods
  • Chemical Cell Biology
    • Cellular imaging
    • Proteomics
  • Biotechnology
    • Protein engineering
  • Computational Chemistry
    • Protein modeling

Therapeutic Areas

  • Cancer
  • Immunology
  • Virology

Prof. Michael RoutThe Rout lab studies nuclear pore complexes (NPCs), which provide the only known sites for nucleocytoplasmic exchange and are also involved in key steps of genetic regulation. Using a variety of techniques, we are determining the structure and mechanisms of the NPC, in order to understand how the NPC functions as a transporter and regulates nuclear processes. We have leveraged techniques developed during these investigations into general tools and reagents for interactomic investigations of cellular systems. Though our collaborative center, the National Center for Dynamic Interactome Research, we train and disseminate these techniques to the biomedical community.

Read more about Prof. Rout’s research on the Rockefeller website

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