TPCB Faculty
Kaavya Krishna Kumar, PhD
Weill Cornell Medicine
Education
PhD, xxxx, University of Sydney
MS, xxxx, Sri Ramachandra Medical College & Research Institute
BS, xxxx, Stella Maris College (Autonomous)
Research Topics
- Bioactive Small Molecules
- Rational drug design
- Macromolecular Structure and Function
- X-ray crystallography
- Cryo-electron microscopy
- Single molecule methods
- Biotechnology
- Protein engineering
Therapeutic Areas
- Cancer
- Diabetes
- Immunology
Cells constantly interpret and respond to environmental cues, and G protein–coupled receptors (GPCRs) are central to this process. The Krishna Kumar lab investigates how GPCRs sense external signals and integrate multiple pathways to produce context-dependent cellular outcomes. Using structural biology, biophysical methods, chemical biology, and protein engineering, we examine how receptor conformations, protein assemblies, and ligand diversity shape signaling specificity. Our goal is to uncover the molecular principles of receptor modulation and apply these insights to design chemical probes and therapeutic strategies that selectively control signaling across physiological and disease contexts.
Read more about Prof. Krishna Kumar’s research on the Weill Cornell website