TPCB Faculty
John Chodera, PhD
Memorial Sloan Kettering Cancer Center
Education
PhD, 2006, University of California, San Francisco
BS, 1999, California Institute of Technology
Research Topics
- Bioactive Small Molecules
- Rational drug design
- High-throughput screening assays
- Macromolecular Structure and Function
- Biotechnology
- Protein engineering
- Computational Chemistry
- Cheminformatics
- Docking
- Protein modeling
Therapeutic Areas
- Cancer
- Virology
- General drug design
The Chodera lab uses computation and experiments to develop quantitative, multiscale models of the effects of small molecules on biomolecular macromolecules and cellular pathways. To do this, the group utilizes physical models and rigorous statistical mechanics, with the overall goals of engineering novel therapeutics and tools for chemical biology, as well as understanding the physical driving forces behind ligand recognition the evolution of resistance mutations.
Read more about Prof. Chodera’s research on the Sloan Kettering website