TPCB Faculty
Alex Kentsis, MD, PhD
Memorial Sloan Kettering Cancer Center
kentsisresearchgroup@gmail.com
Education
MD, 2006, Mount Sinai School of Medicine
PhD, 2004, New York University
SM, 1998, The University of Chicago
AB, 1998, The University of Chicago
Research Topics
- Bioactive Small Molecules
- Rational drug design
- Macromolecular Structure and Function
- Chemical Cell Biology
- Proteomics
- Biotechnology
- Protein engineering
- Computational Chemistry
Therapeutic Areas
- Cancer
The Kentsis lab’s studies in pediatric oncology and cancer biology are focused on cellular plasticity, a phenomenon that relates both to the fundamental mechanisms of cancer pathogenesis and to the development of improved rational therapies. We are interested in understanding the principles by which the genomes and proteomes of tumors are disorganized, and in determining the molecular mechanisms of response and adaptation of tumor cells to targeted therapies.
Read more about Prof. Kentsis’s research on the Sloan Kettering website