Publications
Student publications at the forefront of chemical biology
TPCB students have an exceptional publication record, averaging over 5 papers per PhD graduate! This prolific group has published over 550 scientific papers since 2003, in high impact journals including Nature, Science, Cell, Journal of the American Chemical Society, ACS Chemical Biology, Biochemistry, Cell Chemical Biology, Nature Chemical Biology, and Proceedings of the National Academy of Sciences. Because of our highly interactive research environment, many of these papers involve multidisciplinary collaborations between TPCB laboratories as well as with other researchers on the Tri-Institutional campuses. In total, TPCB labs have published over 200 papers together!
| Name | Publications |
|---|---|
| Banerjee, Anoosha | Small, G. I.; Fedorova, O.; Olinares, P. D. B.; Chandanani, J.; Banerjee, A.; Choi, Y. J.; Molina, H.; Chait, B. T.; Darst, S. A.; Campbell, E. A. Structural and functional insights into the enzymatic plasticity of the SARS-CoV-2 NiRAN domain. Mol. Cell 2023, 83, 3921-3930.e7. DOI: 10.1016/j.molcel.2023.10.001 PMID: 37890482 |
| Grimes, S. L.; Choi, Y. J.; Banerjee, A.; Small, G.; Anderson-Daniels, J.; Gribble, J.; Pruijssers, A. J.; Agostini, M. L.; Abu-Shmais, A.; Lu, X.; Darst, S. A.; Campbell, E.; Denison, M. R. A mutation in the coronavirus nsp13-helicase impairs enzymatic activity and confers partial remdesivir resistance. mBio 2023, 14, e0106023. DOI: 10.1128/mbio.01060-23 PMID: 37338298 | |
| Banerjee, Sourabh | Menon, I.; Huber, T.; Sanyal, S.; Banerjee, S.; Barré, P.; Canis, S.; Warren, J. D.; Hwa, J.; Sakmar, T. P.; Menon, A. K. Opsin is a phospholipid flippase. Curr. Biol. 2011, 21, 149–153. DOI: 10.1016/j.cub.2010.12.031 PMID: 21236677 |
| Knepp, A. M.; Grunbeck, A.; Banerjee, S.; Sakmar, T. P.; Huber, T. Direct measurement of thermal stability of expressed CCR5 and stabilization by small molecule ligands. Biochemistry 2011, 50, 502–511. DOI: 10.1021/bi101059w PMID: 21155586 | |
| Zaitseva, E.; Saavedra, M.; Banerjee, S.; Sakmar, T. P.; Vogel, R. SEIRA spectroscopy on a membrane receptor monolayer using lipoprotein particles as carriers. Biophys. J. 2010, 99, 2327–2335. DOI: 10.1016/j.bpj.2010.06.054 PMID: 20923668 | |
| Banerjee, S.; Huber, T.; Sakmar, T. P. Rapid incorporation of functional rhodopsin into nanoscale apolipoprotein bound bilayer (NABB) particles. J. Mol. Biol. 2008, 377, 1067–1081. DOI: 10.1016/j.jmb.2008.01.066 PMID: 18313692 | |
| Baca, Christian | Hossain, A. A.; Pigli, Y. Z.; Baca, C. F.; Heissel, S.; Thomas, A.; Libis, V. K.; Burian, J.; Chappie, J. S.; Brady, S. F.; Rice, P. A.; Marraffini, L. A. DNA glycosylases provide antiviral defence in prokaryotes. Nature 2024, 629, 410–416. DOI: 10.1038/s41586-024-07329-9 PMID: 38632404 |
| Baca, C. F.; Yu, Y.; Rostøl, J. T.; Majumder, P.; Patel, D. J.; Marraffini, L. A. The CRISPR effector Cam1 mediates membrane depolarization for phage defence. Nature 2024, 625, 797–804. DOI: 10.1038/s41586-023-06902-y PMID: 38200316 | |
| Banik, Jacob | Charlop-Powers, Z.; Banik, J. J.; Owen, J. G.; Craig, J. W.; Brady, S. F. Selective enrichment of environmental DNA libraries for genes encoding nonribosomal peptides and polyketides by phosphopantetheine transferase-dependent complementation of siderophore biosynthesis. ACS Chem. Biol. 2013, 8, 138–143. DOI: 10.1021/cb3004918 PMID: 23072412 |
| Bick, M. J.; Banik, J. J.; Darst, S. A.; Brady, S. F. The 2.7 Å resolution structure of the glycopeptide sulfotransferase Teg14. Acta Crystallogr. D Biol. Crystallogr. 2010, 66, 1278–1286. DOI: 10.1107/S0907444910036681 PMID: 21123867 | |
| Banik, J. J.; Craig, J. W.; Calle, P. Y.; Brady, S. F. Tailoring enzyme-rich environmental DNA clones: a source of enzymes for generating libraries of unnatural natural products. J. Am. Chem. Soc. 2010, 132, 15661–15670. DOI: 10.1021/ja105825a PMID: 20945895 | |
| Banik, J. J.; Brady, S. F. Recent application of metagenomic approaches toward the discovery of antimicrobials and other bioactive small molecules. Curr. Opin. Microbiol. 2010, 13, 603–609. DOI: 10.1016/j.mib.2010.08.012 PMID: 20884282 | |
| Bick, M. J.; Banik, J. J.; Darst, S. A.; Brady, S. F. Crystal structures of the glycopeptide sulfotransferase Teg12 in a complex with the teicoplanin aglycone. Biochemistry 2010, 49, 4159–4168. DOI: 10.1021/bi100150v PMID: 20361791 | |
| Banik, J. J.; Brady, S. F. Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary. Proc. Natl. Acad. Sci. U.S.A. 2008, 105, 17273–17277. DOI: 10.1073/pnas.0807564105 PMID: 18987322 | |
| Bauer, Renato | Wenderski, T. A.; Stratton, C. F.; Bauer, R. A.; Kopp, F.; Tan, D. S. Principal component analysis as a tool for library design: a case study investigating natural products, brand-name drugs, natural product-like libraries, and drug-like libraries. Methods Mol. Biol. 2015, 1263, 225–242. DOI: 10.1007/978-1-4939-2269-7_18 PMID: 25618349 |
| Bauer, R. A.; Wenderski, T. A.; Tan, D. S. Biomimetic diversity-oriented synthesis of benzannulated medium rings via ring expansion. Nat. Chem. Biol. 2012, 9, 21–29. DOI: 10.1038/nchembio.1130 PMID: 23160003 | |
| Moura-Letts, G.; DiBlasi, C. M.; Bauer, R. A.; Tan, D. S. Solid-phase synthesis and chemical space analysis of a 190-membered alkaloid/terpenoid-like library. Proc. Natl. Acad. Sci. U.S.A. 2011, 108, 6745–6750. DOI: 10.1073/pnas.1015268108 PMID: 21451137 | |
| Bauer, R. A.; DiBlasi, C. M.; Tan, D. S. The tert-butylsulfinamide lynchpin in transition-metal-mediated multiscaffold library synthesis. Org. Lett. 2010, 12, 2084–2087. DOI: 10.1021/ol100574y PMID: 20356070 | |
| Bauer, R. A.; Wurst, J. M.; Tan, D. S. Expanding the range of ‘druggable’ targets with natural product-based libraries: an academic perspective. Curr. Opin. Chem. Biol. 2010, 14, 308–314. DOI: 10.1016/j.cbpa.2010.02.001 PMID: 20202892 | |
| Berman, Adi | Kelley, M. E.; Berman, A. Y.; Stirling, D. R.; Cimini, B. A.; Han, Y.; Singh, S.; Carpenter, A. E.; Kapoor, T. M.; Way, G. P. High-content microscopy reveals a morphological signature of bortezomib resistance. eLife 2023, 12, e91362. DOI: 10.7554/eLife.91362 PMID: 37753907 |
| Berman, A. Y.; Wieczorek, M.; Aher, A.; Olinares, P. D. B.; Chait, B. T.; Kapoor, T. M. A nucleotide binding-independent role for γ-tubulin in microtubule capping and cell division. J. Cell. Biol. 2023, 222, e202204102. DOI: 10.1083/jcb.202204102 PMID: 36695784 | |
| Blum, Gil | Chen, S.†; Wiewiora, R. P.†; Meng, F.; Babault, N.; Ma, A.; Yu, W.; Qian, K.; Hu, H.; Zou, H.; Wang, J.; Fan, S.; Blum, G.; Pittella-Silva, F.; Beauchamp, K. A.; Tempel, W.; Jiang, H.; Chen, K.; Skene, R. J.; Zheng, Y. G.; Brown, P. J.; Jin, J.; Luo, C.; Chodera, J. D.; Luo, M. The dynamic conformational landscape of the protein methyltransferase SETD8. eLife 2019, 8, e45403. DOI: 10.7554/eLife.45403 PMID: 31081496 |
| Linscott, J. A.; Kapilashrami, K.; Wang, Z.; Senevirathne, C.; Bothwell, I. R.; Blum, G.; Luo, M. Kinetic isotope effects reveal early transition state of protein lysine methyltransferase SET8. Proc. Natl. Acad. Sci. U.S.A. 2016, 113, E8369-E8378. DOI: 10.1073/pnas.1609032114 PMID: 27940912 | |
| LaFave, L. M.; Béguelin, W.; Koche, R.; Teater, M.; Spitzer, B.; Chramiec, A.; Papalexi, E.; Keller, M. D.; Hricik, T.; Konstantinoff, K.; Micol, J. B.; Durham, B.; Knutson, S. K.; Campbell, J. E.; Blum, G.; Shi, X.; Doud, E. H.; Krivtsov, A. V.; Chung, Y. R.; Khodos, I.; de Stanchina, E.; Ouerfelli, O.; Adusumilli, P. S.; Thomas, P. M.; Kelleher, N. L.; Luo, M.; Keilhack, H.; Abdel-Wahab, O.; Melnick, A.; Armstrong, S. A.; Levine, R. L. Loss of BAP1 function leads to EZH2-dependent transformation. Nat. Med. 2015, 21, 1344–1349. DOI: 10.1038/nm.3947 PMID: 26437366 | |
| Blum, G.; Ibáñez, G.; Rao, X.; Shum, D.; Radu, C.; Djaballah, H.; Rice, J. C.; Luo, M. Small-molecule inhibitors of SETD8 with cellular activity. ACS Chem. Biol. 2014, 9, 2471–2478. DOI: 10.1021/cb500515r PMID: 25137013 | |
| Guo, H.; Wang, R.; Zheng, W.; Chen, Y.; Blum, G.; Deng, H.; Luo, M. Profiling substrates of protein arginine N-methyltransferase 3 with S-adenosyl-L-methionine analogues. ACS Chem. Biol. 2014, 9, 476–484. DOI: 10.1021/cb4008259 PMID: 24320160 | |
| Islam, K.; Chen, Y.; Wu, H.; Bothwell, I. R.; Blum, G. J.; Zeng, H.; Dong, A.; Zheng, W.; Min, J.; Deng, H.; Luo, M. Defining efficient enzyme-cofactor pairs for bioorthogonal profiling of protein methylation. Proc. Natl. Acad. Sci. U.S.A. 2013, 110, 16778–16783. DOI: 10.1073/pnas.1216365110 PMID: 24082136 | |
| Blum, G.; Bothwell, I. R.; Islam, K.; Luo, M. Profiling protein methylation with cofactor analog containing terminal alkyne functionality. Curr. Protoc. Chem. Biol. 2013, 5, 67–88. DOI: 10.1002/9780470559277.ch120241 PMID: 23788324 | |
| Blum, G.; Islam, K.; Luo, M. Bioorthogonal profiling of protein methylation (BPPM) using an azido analog of S-adenosyl-L-methionine. Curr. Protoc. Chem. Biol. 2013, 5, 45–66. DOI: 10.1002/9780470559277.ch120240 PMID: 23667794 | |
| Wang, R.; Islam, K.; Liu, Y.; Zheng, W.; Tang, H.; Lailler, N.; Blum, G.; Deng, H.; Luo, M. Profiling genome-wide chromatin methylation with engineered posttranslation apparatus within living cells. J. Am. Chem. Soc. 2013, 135, 1048–1056. DOI: 10.1021/ja309412s PMID: 23244065 | |
| Zheng, W.; Ibáñez, G.; Wu, H.; Blum, G.; Zeng, H.; Dong, A.; Li, F.; Hajian, T.; Allali-Hassani, A.; Amaya, M. F.; Siarheyeva, A.; Yu, W.; Brown, P. J.; Schapira, M.; Vedadi, M.; Min, J.; Luo, M. Sinefungin derivatives as inhibitors and structure probes of protein lysine methyltransferase SETD2. J. Am. Chem. Soc. 2012, 134, 18004–18014. DOI: 10.1021/ja307060p PMID: 23043551 | |
| Bothwell, I. R.; Islam, K.; Chen, Y.; Zheng, W.; Blum, G.; Deng, H.; Luo, M. Se-adenosyl-L-selenomethionine cofactor analogue as a reporter of protein methylation. J. Am. Chem. Soc. 2012, 134, 14905–14912. DOI: 10.1021/ja304782r PMID: 22917021 | |
| Ibanez, G.; Shum, D.; Blum, G.; Bhinder, B.; Radu, C.; Antczak, C.; Luo, M.; Djaballah, H. A high throughput scintillation proximity imaging assay for protein methyltransferases. Comb. Chem. High Throughput Screen. 2012, 15, 359–371. DOI: 10.2174/138620712800194468 PMID: 22256970 | |
| Wang, R.; Ibáñez, G.; Islam, K.; Zheng, W.; Blum, G.; Sengelaub, C.; Luo, M. Formulating a fluorogenic assay to evaluate S-adenosyl-L-methionine analogues as protein methyltransferase cofactors. Mol. Biosyst. 2011, 7, 2970–2981. DOI: 10.1039/c1mb05230f PMID: 21866297 | |
| Bose, Neelanjan | Shinoda, K.; Choe, A.; Hirahara, K.; Kiuchi, M.; Kokubo, K.; Ichikawa, T.; Hoki, J. S.; Suzuki, A. S.; Bose, N.; Appleton, J. A.; Aroian, R. V.; Schroeder, F. C.; Sternberg, P. W.; Nakayama, T. Nematode ascarosides attenuate mammalian type 2 inflammatory responses. Proc Natl Acad Sci U S A 2022, 119, e2108686119. DOI: 10.1073/pnas.2108686119 PMID: 35210367 |
| Falcke, J. M.†; Bose, N.†; Artyukhin, A. B.; Rödelsperger, C.; Markov, G. V.; Yim, J. J.; Grimm, D.; Claassen, M. H.; Panda, O.; Baccile, J. A.; Zhang, Y. K.; Le, H. H.; Jolic, D.; Schroeder, F. C.; Sommer, R. J. Linking genomic and metabolomic natural variation uncovers nematode pheromone biosynthesis. Cell Chem. Biol. 2018, 25, 787–796. DOI: 10.1016/j.chembiol.2018.04.004 PMID: 29779955 | |
| Liu, Z.; Kariya, M. J.; Chute, C. D.; Pribadi, A. K.; Leinwand, S. G.; Tong, A.; Curran, K. P.; Bose, N.; Schroeder, F. C.; Srinivasan, J.; Chalasani, S. H. Predator-secreted sulfolipids induce defensive responses in C. elegans. Nat. Commun. 2018, 9, 1128. DOI: 10.1038/s41467-018-03333-6 PMID: 29555902 | |
| Narayan, A.; Venkatachalam, V.; Durak, O.; Reilly, D. K.; Bose, N.; Schroeder, F. C.; Samuel, A. D.; Srinivasan, J.; Sternberg, P. W. Contrasting responses within a single neuron class enable sex-specific attraction in Caenorhabditis elegans. Proc. Natl. Acad. Sci. U.S.A. 2016, 113, E1392–E1401. DOI: 10.1073/pnas.1600786113 PMID: 26903633 | |
| Chaudhuri, J.; Bose, N.; Tandonnet, S.; Adams, S.; Zuco, G.; Kache, V.; Parihar, M.; von Reuss, S. H.; Schroeder, F. C.; Pires-daSilva, A. Mating dynamics in a nematode with three sexes and its evolutionary implications. Sci. Rep. 2015, 5, 17676. DOI: 10.1038/srep17676 PMID: 26631423 | |
| Yim, J. J.; Bose, N.; Meyer, J. M.; Sommer, R. J.; Schroeder, F. C. Nematode signaling molecules derived from multimodular assembly of primary metabolic building blocks. Org. Lett. 2015, 17, 1648–1651. DOI: 10.1021/acs.orglett.5b00329 PMID: 25782998 | |
| Zugasti, O.; Bose, N.; Squiban, B.; Belougne, J.; Kurz, C. L.; Schroeder, F. C.; Pujol, N.; Ewbank, J. J. Activation of a G protein-coupled receptor by its endogenous ligand triggers the innate immune response of Caenorhabditis elegans. Nat. Immunol. 2014, 15, 833–838. DOI: 10.1038/ni.2957 PMID: 25086774 | |
| Bose, N.; Meyer, J. M.; Yim, J. J.; Mayer, M. G.; Markov, G. V.; Ogawa, A.; Schroeder, F. C.; Sommer, R. J. Natural variation in dauer pheromone production and sensing supports intraspecific competition in nematodes. Curr. Biol. 2014, 24, 1536–1541. DOI: 10.1016/j.cub.2014.05.045 PMID: 24980503 | |
| Mahanti, P.; Bose, N.; Bethke, A.; Judkins, J. C.; Wollam, J.; Dumas, K. J.; Zimmerman, A. M.; Campbell, S. L.; Hu, P. J.; Antebi, A.; Schroeder, F. C. Comparative metabolomics reveals endogenous ligands of DAF-12, a nuclear hormone receptor, regulating C. elegans development and lifespan. Cell Metab. 2014, 19, 73–83. DOI: 10.1016/j.cmet.2013.11.024 PMID: 24411940 | |
| Artyukhin, A. B.; Yim, J. J.; Srinivasan, J.; Izrayelit, Y.; Bose, N.; von Reuss, S. H.; Jo, Y.; Jordan, J. M.; Baugh, L. R.; Cheong, M.; Sternberg, P. W.; Avery, L.; Schroeder, F. C. Succinylated octopamine ascarosides and a new pathway of biogenic amine metabolism in Caenorhabditis elegans. J. Biol. Chem. 2013, 288, 18778–18783. DOI: 10.1074/jbc.C113.477000 PMID: 23689506 | |
| Izrayelit, Y.; Robinette, S. L.; Bose, N.; von Reuss, S. H.; Schroeder, F. C. 2D NMR-based metabolomics uncovers interactions between conserved biochemical pathways in the model organism Caenorhabditis elegans. ACS Chem. Biol. 2013, 8, 314–319. DOI: 10.1021/cb3004644 PMID: 23163760 | |
| Bose, N.; Ogawa, A.; von Reuss, S. H.; Yim, J. J.; Ragsdale, E. J.; Sommer, R. J.; Schroeder, F. C. Complex small-molecule architectures regulate phenotypic plasticity in a nematode. Angew. Chem. Int. Ed. Engl. 2012, 51, 12438–12443. DOI: 10.1002/anie.201206797 PMID: 23161728 | |
| Srinivasan, J.; von Reuss, S. H.; Bose, N.; Zaslaver, A.; Mahanti, P.; Ho, M. C.; O’Doherty, O. G.; Edison, A. S.; Sternberg, P. W.; Schroeder, F. C. A modular library of small molecule signals regulates social behaviors in Caenorhabditis elegans. PLoS Biol. 2012, 10, e1001237. DOI: 10.1371/journal.pbio.1001237 PMID: 22253572 | |
| von Reuss, S. H.; Bose, N.; Srinivasan, J.; Yim, J. J.; Judkins, J. C.; Sternberg, P. W.; Schroeder, F. C. Comparative metabolomics reveals biogenesis of ascarosides, a modular library of small-molecule signals in C. elegans. J. Am. Chem. Soc. 2012, 134, 1817–1824. DOI: 10.1021/ja210202y PMID: 22239548 | |
| Bothwell, Ian | Shu, X.; Dai, Q.; Wu, T.; Bothwell, I. R.; Yue, Y.; Zhang, Z.; Cao, J.; Fei, Q.; Luo, M.; He, C.; Liu, J. N6-Allyladenosine: A new small molecule for RNA labeling identified by mutation assay. J. Am. Chem. Soc. 2017, 139, 17213–17216. DOI: 10.1021/jacs.7b06837 PMID: 29116772 |
| Linscott, J. A.; Kapilashrami, K.; Wang, Z.; Senevirathne, C.; Bothwell, I. R.; Blum, G.; Luo, M. Kinetic isotope effects reveal early transition state of protein lysine methyltransferase SET8. Proc. Natl. Acad. Sci. U.S.A. 2016, 113, E8369-E8378. DOI: 10.1073/pnas.1609032114 PMID: 27940912 | |
| Bothwell, I. R.; Luo, M. Large-scale, protection-free synthesis of Se-adenosyl-L-selenomethionine analogues and their application as cofactor surrogates of methyltransferases. Org. Lett. 2014, 16, 3056–3059. DOI: 10.1021/ol501169y PMID: 24852128 | |
| Islam, K.; Chen, Y.; Wu, H.; Bothwell, I. R.; Blum, G. J.; Zeng, H.; Dong, A.; Zheng, W.; Min, J.; Deng, H.; Luo, M. Defining efficient enzyme-cofactor pairs for bioorthogonal profiling of protein methylation. Proc. Natl. Acad. Sci. U.S.A. 2013, 110, 16778–16783. DOI: 10.1073/pnas.1216365110 PMID: 24082136 | |
| Winter, J. M.; Chiou, G.; Bothwell, I. R.; Xu, W.; Garg, N. K.; Luo, M.; Tang, Y. Expanding the structural diversity of polyketides by exploring the cofactor tolerance of an inline methyltransferase domain. Org. Lett. 2013, 15, 3774–3777. DOI: 10.1021/ol401723h PMID: 23837609 | |
| Blum, G.; Bothwell, I. R.; Islam, K.; Luo, M. Profiling protein methylation with cofactor analog containing terminal alkyne functionality. Curr. Protoc. Chem. Biol. 2013, 5, 67–88. DOI: 10.1002/9780470559277.ch120241 PMID: 23788324 | |
| Bothwell, I. R.; Islam, K.; Chen, Y.; Zheng, W.; Blum, G.; Deng, H.; Luo, M. Se-adenosyl-L-selenomethionine cofactor analogue as a reporter of protein methylation. J. Am. Chem. Soc. 2012, 134, 14905–14912. DOI: 10.1021/ja304782r PMID: 22917021 | |
| Islam, K.; Bothwell, I.; Chen, Y.; Sengelaub, C.; Wang, R.; Deng, H.; Luo, M. Bioorthogonal profiling of protein methylation using azido derivative of S-adenosyl-L-methionine. J. Am. Chem. Soc. 2012, 134, 5909–5915. DOI: 10.1021/ja2118333 PMID: 22404544 | |
| Burnside, Chloe | Harper, N. J.†; Burnside, C.†; Klinge, S. Principles of mitoribosomal small subunit assembly in eukaryotes. Nature 2023, 614, 175–181. DOI: 10.1038/s41586-022-05621-0 PMID: 36482135 |
| Cahir, Clare | Yang, L.; Han, Y.; Zhou, T.; Lacko, L. A.; Saeed, M.; Tan, C.; Danziger, R.; Zhu, J.; Zhao, Z.; Cahir, C.; Giana, A. M.; Li, Y.; Dong, X.; Moroziewicz, D.; NYSCF Global Stem Cell Array® Team; Paull, D.; Chen, Z.; Zhong, A.; Noggle, S. A.; Rice, C. M.; Qi, Q.; Evans, T.; Chen, S. Isogenic human trophectoderm cells demonstrate the role of NDUFA4 and associated variants in ZIKV infection. iScience 2023, 26, 107001. DOI: 10.1016/j.isci.2023.107001 PMID: 37534130 |
| Han, Y.; Tan, L.; Zhou, T.; Yang, L.; Carrau, L.; Lacko, L. A.; Saeed, M.; Jiajun, Z.; Zhao, Z.; Nilsson-Payant, B. E.; Tenorio Lira Neto, F.; Cahir, C.; Giana, A. M.; Chai, J. C.; Li, Y.; Dong, X.; Moroziewicz, D.; NYSCF Global Stem Cell Array Team; Paull, D; Zhang, T.; Koo, S.; Tan, C.; Danziger, R.; Ba, Q.; Feng, L; Chen, Z.; Zhong, A.; Wise, G. J.; Xiang, J. Z.; Wang, H.; Schwartz, R. E.; tenOever, B. R.; Noggle, S. A.; Rice, C. M.; Qi, Q.; Evans, T.; Chen, S. A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants. Cell Stem Cell 2022, 29, 1475-1490. DOI: 10.1016/j.stem.2022.09.008 PMID: 36206731 | |
| Carl, Ayala | Reynolds, M. J.; Hachicho, C.; Carl, A. G.; Gong, R.; Alushin, G. M. Bending forces and nucleotide state jointly regulate F-actin structure. Nature 2022, 611, 380–386. DOI: 10.1038/s41586-022-05366-w PMID: 36289330 |
| Uson, M. L.; Carl, A.; Goldgur, Y.; Shuman, S. Crystal structure and mutational analysis of Mycobacterium smegmatis FenA highlight active site amino acids and three metal ions essential for flap endonuclease and 5′ exonuclease activities. Nucleic Acids Res. 2018, 46, 4164–4175. DOI: 10.1093/nar/gky238 PMID: 29635474 | |
| Chaker-Margot, Malik | Singh, S.; Vanden Broeck, A.; Miller, L.; Chaker-Margot, M.; Klinge, S. Nucleolar maturation of the human small subunit processome. Science 2021, 373, eabj5338. DOI: 10.1126/science.abj5338 PMID: 34516797 |
| Chaker-Margot, M.; Klinge, S. Assembly and early maturation of large subunit precursors. RNA 2019, 25, 465–471. DOI: 10.1261/rna.069799.118 PMID: 30670483 | |
| Bolze, A.; Boisson, B.; Bosch, B.; Antipenko, A.; Bouaziz, M.; Sackstein, P.; Chaker-Margot, M.; Barlogis, V.; Briggs, T.; Colino, E.; Elmore, A. C.; Fischer, A.; Genel, F.; Hewlett, A.; Jedidi, M.; Kelecic, J.; Krüger, R.; Ku, C. L.; Kumararatne, D.; Lefevre-Utile, A.; Loughlin, S.; Mahlaoui, N.; Markus, S.; Garcia, J. M.; Nizon, M.; Oleastro, M.; Pac, M.; Picard, C.; Pollard, A. J.; Rodriguez-Gallego, C.; Thomas, C.; Von Bernuth, H.; Worth, A.; Meyts, I.; Risolino, M.; Selleri, L.; Puel, A.; Klinge, S.; Abel, L.; Casanova, J. L. Incomplete penetrance for isolated congenital asplenia in humans with mutations in translated and untranslated RPSA exons. Proc. Natl. Acad. Sci. U.S.A. 2018, 115, E8007–E8016. DOI: 10.1073/pnas.1805437115 PMID: 30072435 | |
| Chaker-Margot, M.* Assembly of the small ribosomal subunit in yeast: Mechanism and regulation. RNA 2018, 24, 881–891. DOI: 10.1261/rna.066985.118 PMID: 29712726 | |
| Sanghai, Z. A.†; Miller, L.†; Molloy, K. R.; Barandun, J.; Hunziker, M.; Chaker-Margot, M.; Wang, J.; Chait, B. T.; Klinge, S. Modular assembly of the nucleolar pre-60S ribosomal subunit. Nature 2018, 556, 126–129. DOI: 10.1038/nature26156 PMID: 29512650 | |
| Barandun, J.†; Chaker-Margot, M.†; Hunziker, M.; Molloy, K. R.; Chait, B. T.; Klinge, S. The complete structure of the small-subunit processome. Nat. Struct. Mol. Biol. 2017, 24, 944–953. DOI: 10.1038/nsmb.3472 PMID: 28945246 | |
| Chaker-Margot, M.; Barandun, J.; Hunziker, M.; Klinge, S. Architecture of the yeast small subunit processome. Science 2017, 355, eaal1880. DOI: 10.1126/science.aal1880 PMID: 27980088 | |
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