Weill Cornell Medical College The Rockefeller University Memorial Sloan-Kettering Cancer Center

Apply Online Application Due: December 1, 2013

TPCB Faculty

Yael David, PhD

Memorial Sloan-Kettering Cancer Center

Education

PhD, 2011, Weizmann Institute of Science

BS, 2004, Stony Brook University

Research Topics

  • Bioactive Small Molecules
    • Chemical probe development
  • Macromolecular Structure and Function
    • Enzymology
    • Mass spectrometry
  • Chemical Cell Biology
    • Chemical genetics
    • Cellular imaging
    • Activity-based protein profiling
  • Biotechnology
    • Protein engineering

Therapeutic Areas

  • Cancer
  • Diabetes

photoResearch efforts in the David lab apply core techniques in chemical biology, biochemistry, and cell biology to address fundamental questions in the epigenetic regulation of transcription. Epigenetic regulation relies on the dynamic modification of the two building blocks of chromatin: DNA and histone packaging proteins, to establish and maintain cell identity and fate. We develop and utilize chemical methods to synthesize site-specifically modified histones in vitro and in vivo and study the roles that these modifications play in disease states, with the ultimate goal of targeting them for therapeutics.

Apply Online!