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TPCB Faculty

Xuejun Jiang, PhD

Memorial Sloan-Kettering Cancer Center

Education

PhD, University of Texas Southwestern Medical Center at Dallas

MA, Fudan University, Shanghai

BS, Fudan University, Shanghai

Research Topics

  • Bioactive Small Molecules
    • High-throughput screening assays
    • Chemical probe development
    • Rational drug design
  • Macromolecular Structure and Function
    • Enzymology
    • Mass spectrometry
  • Chemical Cell Biology
    • Chemical genetics
    • Proteomics
    • Metabolomics

Therapeutic Areas

  • Cancer
  • Cardiovascular
  • Neuroscience

photoResearch in the Jiang lab focuses on three intertwined directions highly relevant to human disease: (1) the molecular basis of programmed cell death, including apoptosis and a newly defined death mode known as ferroptosis; (2) the molecular basis of autophagy; and (3) regulation of the tumor suppressor PTEN, which is also a modulator for both cell death and autophagy. We also aim to translate our basic research finding into potential therapeutic approaches. The laboratory utilizes a combination of approaches including biochemistry, chemical biology, proteomics, molecular cell biology, high-throughput screening, three-dimensional microfluidic cell array, and mouse modeling.

Read more about Prof. Jiang’s research on the Sloan-Kettering website

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