Weill Cornell Medical College The Rockefeller University Memorial Sloan-Kettering Cancer Center

Apply Online Application Due: December 1, 2013

TPCB Faculty

Minkui Luo, PhD

Memorial Sloan-Kettering Cancer Center

Education

PhD, 2005, Princeton University

BA, 1999, Fudan University

Awards

NIH Director’s New Innovator Awardee

Research Topics

  • Bioactive Small Molecules
    • High-throughput screening assays
    • Chemical probe development
  • Macromolecular Structure and Function
    • Enzymology
  • Chemical Cell Biology
    • Chemical genetics
    • Proteomics
    • Activity-based protein profiling
  • Biotechnology
    • Protein engineering

Therapeutic Areas

  • Cancer
  • Neuroscience

photoThe projects in the Luo lab aim to provide new chemical genetic tools to define, perturb and manipulate essential functions of the enzymes involving protein posttranslational modification (methyltransferases and acetyltransferases). Another focus is to design and synthesize tight-binding inhibitors as anti-cancer drug candidates by blocking these protein-modifying activities. Researchers in the fields of chemistry, biology and biochemistry work together closely to synthesize novel chemical reagents, elucidate illness-causing mechanisms at molecular level and develop potential treatments for human diseases.

Read more about Prof. Luo’s research on the Sloan-Kettering website

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