Weill Cornell Medical College The Rockefeller University Memorial Sloan-Kettering Cancer Center

Apply Online Application Due: December 1, 2013

TPCB Faculty

Gregory Alushin, PhD

Rockefeller University

Education

PhD, 2012, University of California, Berkeley

BA, 2006, Columbia University

Research Topics

  • Macromolecular Structure and Function
    • Cryo-electron microscopy
    • Single molecule methods
  • Chemical Cell Biology
    • Cellular imaging
  • Biotechnology
    • Protein engineering

Therapeutic Areas

  • Cancer
  • Cardiovascular

photoCells in our bodies are constantly subjected to mechanical forces, which impact cellular decision-making (differential gene expression) in development and disease. The Alushin lab is investigating how forces modulate the conformation of macromolecular assemblies, in particular cytoskeletal filaments, to regulate binding interactions which transduce mechanical cues into chemical signaling pathways. We are developing technology for elucidating the structures of macromolecules under load with cryo-electron microscopy, as well as employing fluorescence-based methods to visualize the dynamics of these processes in vitro and in cells.

Read more about Prof. Alushin’s research on the Rockefeller website

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