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TPCB Faculty

Christopher Lima, PhD

Memorial Sloan-Kettering Cancer Center

Education

PhD, 1994, Northwestern University

BA, 1989, The Ohio State University

Awards

HHMI Investigator

Research Topics

  • Macromolecular Structure and Function
    • Enzymology
    • X-ray crystallography

photoThe Lima lab studies the structural, biochemical, and functional basis for macromolecules involved in post-translational protein modification by SUMO, an ubiquitin-like protein modifier, and pathways that contribute to co-transcriptional RNA maturation and post-transcriptional RNA decay. In addition to our structural studies, our main areas of interest focus on how these pathways contribute to signaling, cell cycle control, nuclear localization, and control of RNA metabolism. We are particularly interested in learning how these pathways contribute to cell growth and disease.

Read more about Prof. Lima’s research on the Sloan-Kettering website

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