TPCB Faculty
Ekaterina Vinogradova, PhD
Rockefeller University
Education
PhD, 2015, Massachusetts Institute of Technology
MSc, 2010, Russian Academy of Sciences
Research Topics
- Bioactive Small Molecules
- Rational drug design
- High-throughput screening assays
- Chemical probe development
- Chemical Cell Biology
- Proteomics
- Activity-based protein profiling
- Macromolecular Structure and Function
- Enzymology
- Mass spectrometry
Therapeutic Areas
- Cancer
- Immunology
- Neuroscience
- Microbiology
The Vinogradova lab applies synthetic chemistry, chemical biology, and proteomics methods towards the goals of discovering and characterizing (a) novel selective chemical probes that perturb the functions of key proteins regulating immunological and neuroimmunological processes; (b) new mechanisms for small molecule-induced protein degradation; and, more broadly, (c) the pharmacological landscape and signal transduction pathways in immune and neuroimmunological disorders. Achieving these objectives is enhanced through the development of new chemical scaffolds targeting cysteine and other nucleophilic residues.
Read more about Prof. Vinogradova’s research on the Rockefeller website